Th e increased understanding of blood diseases particularly their genetic basis and changes in their treatment is such that in writing this new edition, substantial changes have been necessary throughout. Th e classifi cation of the neoplasms of the haemopoietic and lymphoid diseases has been revised by WHO and the names and defi nitions of many of these diseases have changed. Clinical features, genetics and immunophenotype are increasingly used to defi ne biological entities. We have made changes in all the relevant chapters but, in a book intended primarily for undergraduates, we have simplifi ed some of the classifi cation tables and omitted detailed descriptions of rare diseases. On the other hand, some tests e. As previously, we have used a colour line in the margin to indicate text that we consider more advanced than is needed for under graduate medical students and more appropriate for postgraduates.

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Th e increased understanding of blood diseases particularly their genetic basis and changes in their treatment is such that in writing this new edition, substantial changes have been necessary throughout. Th e classifi cation of the neoplasms of the haemopoietic and lymphoid diseases has been revised by WHO and the names and defi nitions of many of these diseases have changed.
Clinical features, genetics and immunophenotype are increasingly used to defi ne biological entities. We have made changes in all the relevant chapters but, in a book intended primarily for undergraduates, we have simplifi ed some of the classifi cation tables and omitted detailed descriptions of rare diseases. On the other hand, some tests e. As previously, we have used a colour line in the margin to indicate text that we consider more advanced than is needed for under graduate medical students and more appropriate for postgraduates.
John Pettit, co — author on all fi ve previous editions, has retired from authorship for this edition. Many of these images appear in this latest edition. Th e diff erent aspects of iron overload are now merged into a new chapter and we have separated chapters on acute myeloid and acute lymphoblastic leukaemia.
We have also introduced summary boxes at the end of each chapter to summarise the contents and added multiple choice questions to the website both at undergraduate and at a more advanced level to help in self — learning.
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